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Literature summary extracted from
- Radical reaction control in the AdoMet radical enzyme CDG synthase (QueE) consolidate, destabilize, accelerate (2017), Chemistry, 23, 953-962 .
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.3.99.3 | Mg2+ | the Mg2+ complexation not only brings the substrate into the reactive conformation but also, once a hydrogen atom is abstracted from the substrate, holds the resultant intermediate radical in a highly strained conformation | Burkholderia multivorans |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.3.99.3 | Burkholderia multivorans | A0A0H3KB22 | - |
- |
| 4.3.99.3 | Burkholderia multivorans ATCC 17616 | A0A0H3KB22 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.3.99.3 | 6-carboxy-5,6,7,8-tetrahydropterin | - |
Burkholderia multivorans | 7-carboxy-7-carbaguanine + NH3 | - |
? | |
| 4.3.99.3 | 6-carboxy-5,6,7,8-tetrahydropterin | - |
Burkholderia multivorans ATCC 17616 | 7-carboxy-7-carbaguanine + NH3 | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.3.99.3 | CDG synthase | - |
Burkholderia multivorans |
| 4.3.99.3 | queE | - |
Burkholderia multivorans |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.3.99.3 | S-adenosyl-L-methionine | S-adenosyl-L-methionine-dependent radical enzyme | Burkholderia multivorans | |
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Release 2023.1 (January 2023)
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